Gregory D. Fink, PhD
- Faculty, Training Faculty, Behavioral & Systems
Professor, Pharmacology & Toxicology
Ph.D., 1975, Tulane University
Research in my laboratory focuses on the causes of cardiovascular disease, especially systemic hypertension. A major emphasis is on how sympathetic nerves affect short-term and long-term regulation of the cardiovascular system. We study both brain and peripheral autonomic mechanisms using pharmacological tools in conscious rats and mice. A particular interest is in how the hormones angiotensin II and endothelin influence sympathetic nerve function. Recently we started a collaborative research effort with several other MSU investigators to explore the differences in neurohormonal control of arteries versus veins. The role of oxidative stress in modulating neural and vascular function is a current emphasis. Our ultimate goal is to develop new therapeutic approaches to cardiovascular disease by targeting the sympathetic nerves innervating the veins.